L-PRF vs I-PRF how are these Platelet Rich Fibrin treatments different?
PRF is an extract of patients blood. It is made by spinning samples of blood in a centrifuge. PRF is used for dental implants, bone grafting, gum grafting and treating infections in bone. These rich platelet techniques are very useful as a stand alone treatment or in conjunction with other bone graft products. Sticky bone is a graft therapy consisting of L-PRF, allograft bone and I-PRF. Since PRF comes from the patient, there is a 0% chance of rejection when using it as the only bone graft material. PRF is the grafting material of choice in patients with lots of allergies, sensitivities and biocompatibility issues. Platelet rich fibrin improves the success rates of full mouth implant cases and snap on implant dentures.
PRF has a synergistic effect with allograft off-the-shelf graft products. PRF contains BMP or bone morphogenic protein. Through biological pathways BMP stimulates the bone cells to naturally grow more bone rapidly. Off the shelf products will slowly over time be converted to host bone. The two treatments together create a “biological bone graft” in that the allograft shows the bone cells where to grow bone. And the PRF stimulates the bodies bone cells to rapidly grow bone.
PRF has a mixture:
- white blood cells
- bone morphogenic protein or BMP
- stem cells
- skin or gum growth factors
What is L-PRF?
L-PRF is the most widely used for bone grafting, socket preservation and gum grafting. Basically blood samples are spun in a centrifuge at 2700 – 3000 RPMs for 10 – 15 minutes. The result is a thick clotted yellow jello like substance called “PRF.” When the reference to “PRF” is made, most of the time the reference is to L-PRF. PRF is invaluable in helping infected root canal removal sites.
What is I-PRF?
I-PRF is so called “injectable PRF.” It is so called because it is a thinner mixture of unclotted product containing all the same blood products listed above 1-5. I-PRF can be injected because it is not a clotted and is not thick but rather a injectable liquid. I-PRF has an unlimited number of applications including injections into areas where bone grafts have been placed. It can be injected into areas of previous infection, dental implant surgery sites, infected root canal sites. Injectable PRF improves success rates for metal free zirconia implants by using it to wet the implant surface prior to placement into the jaw.